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KMID : 1094020210380010041
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Journal of Veterinary Clinics
2021 Volume.38 No. 1 p.41 ~ p.44
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Pituitary Pars Intermedia Dysfunction with Laminitis in a Horse
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Lee Eun-Bee
Chun Yong-Woo
Park Kyung-Won
Kang Tae-Young
Seo Jong-Pil
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Abstract
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Pituitary pars intermedia dysfunction (PPID), often referred to as equine Cushing's disease, is a common endocrine disorder often diagnosed in older horses. A 13-year-old 460 kg Warmblood gelding showed clinical signs suggestive of PPID, including hypertrichosis, fat redistribution, polyuria and polydipsia (PU/PD), and weight loss. Physical examination, complete blood cell count, and serum chemistry results were normal. However, dexamethasone suppression and plasma adrenocorticotropic hormone (ACTH) level tests confirmed PPID. Three months after the confirmed diagnosis, the horse was referred again with symptoms of laminitis. Radiography and venography were performed to evaluate the laminitis severity level. However, the foot condition continued to worsen, and the horse was eventually euthanized. The purpose of this case report is to describe clinical signs and diagnosis of PPID with laminitis.
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KEYWORD
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pituitary pars intermedia dysfunction, dexamethasone suppression test, laminitis, horse
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